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2F02-01
2022/03/16 09:30
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¿¿¶ÝEupenicillium ludwigiiͳÍèPKS¥Á¥ª¥¨¥¹¥Æ¥é¡¼¥¼ElbB¤Î´ð¼Áǧ¼±µ¡¹½¤Ë´Ø¤¹¤ë¹½Â¤²òÀÏ
Structural analysis of the ligand binding mechanism of the PKS thioesterase ElbB from the fungus Eupenicillium ludwigii
¡û¾®ÎÓ àöÊ¿1¡¢±ÊÅÄ Î´Ê¿1,2¡¢¿¹²¼ ÍÛÊ¿3¡¢¿û¸¶ ¾Ï¸ø3¡¢Àõ°æ Ä÷¸ã3¡¢³ë»³ ÃÒµ×1,4
¡ûYohei KOBAYASHI1, Ryuhei NAGATA1,2, Yohei MORISHITA3, Akihiro SUGAWARA3, Teigo ASAI3, Tomohisa KUZUYAMA1,4
1ÅìÂ籡¡¦ÇÀÀ¸²Ê¡¢2JSPSÆÃÊ̸¦µæ°÷PD¡¢3ÅìËÌÂ籡Ìô¡¢4ÅìÂçCRIIM
1GSALS, UTokyo, 2JSPS Research Fellow, 3GSPS, Tohoku Univ, 4CRIIM, UTokyo
2F02-02
2022/03/16 09:30
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¥Ò¥É¥í¥­¥µ¥à»À´ð¤ÎÀ¸¹çÀ®¤òô¤¦¹ÚÁÇTsnB9¤Î´ð¼Áǧ¼±µ¡¹½¤Ë´Ø¤¹¤ë¸¦µæ
Structural study of the ligand-binding mechanism of TsnB9 that produces a hydroxamic acid group
¡û±ÊÅÄ Î´Ê¿1,2¡¢À¾»³ ¿¿1,3¡¢³ë»³ ÃÒµ×1,3
¡ûRyuhei NAGATA1,2, Makoto NISHIYAMA1,3, Tomohisa KUZUYAMA1,3
1ÅìÂ籡¡¦ÇÀÀ¸²Ê¡¢2³Ø¿¶ÆÃÊ̸¦µæ°÷PD¡¢3ÅìÂ硦CRIIM
1GSALS, UTokyo, 2JSPS Research Fellow, 3CRIIM, UTokyo
2F02-03
2022/03/16 09:30
¥ß¡¼¥Æ¥£¥ó¥°¥ë¡¼¥à F
ÊüÀþ¶ÝͳÍè1-azabicyclo[3.1.0]hexane´Ä´ÞÍ­²½¹çʪ¤Ë¤ª¤±¤ë¥¢¥¸¥ê¥¸¥ó´Ä¹çÀ®µ¡¹½¤Î²òÌÀ
Studies on the aziridine ring formation in 1-azabicyclo[3.1.0]hexane ring biosynthesized in Streptomyces
¡û¹õß· èÁ1¡¢Ä¹Ã«Éô ʸ¿Í1¡¢²¬Â¼ ¿Î§1¡¢µÈÅÄ ºÌ»Ò1,2¡¢ÉÙÅÄ ÉðϺ1,2¡¢ÂìÀî ¹À¶¿1¡¢¸Å±à ¤µ¤ª¤ê1,2¡¢À¾»³ ¿¿1,2
¡ûSumire KUROSAWA1, Fumihito HASEBE1, Hironori OKAMURA1, Ayako YOSHIDA1,2, Takeo TOMITA1,2, Hirosato TAKIKAWA1, Saori KOSONO1,2, Makoto NISHIYAMA1,2
1ÅìÂ硦ÇÀÀ¸²Ê¡¢2ÅìÂ硦ÈùÀ¸ÊªÏ¢·Èµ¡¹½
1Grad. Sch. Agri. & Life Sci., UTokyo, 2CRIIM, UTokyo
2F02-04
2022/03/16 09:30
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¥Ç¥«¥ê¥ó¹çÀ®¹ÚÁǤÎÁ˳²ºÞƱÄê¤È¶¦·ë¾½¹½Â¤²òÀÏ
Inhibitor screening and cocrystal structural analysis of decalin synthases
¡û²ÃÆ£ ľ¼ù1,2¡¢Æ£»³ ·É²ð3¡¢±ÊÌî ¿¿¸ã3¡¢¹â¶¶ ½ÓÆó2
¡ûNaoki KATO1,2, Keisuke FUJIYAMA3, Shingo NAGANO3, Shunji TAKAHASHI2
1ÀÝÆîÂçÇÀ¡¢2Íý¸¦CSRS¡¢3Ä»¼èÂ籡¹©
1Setsunan Univ., 2RIKEN CSRS, 3Tottori Univ.
2F02-05
2022/03/16 09:30
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Reveromycin AÀ¸¹çÀ®¹ÚÁÇRevKLM¤Îin sillico²òÀϤˤè¤ëÁê¸ßºîÍÑͽ¬¤È¼Â¸³Åª¸¡¾Ú
Prediction by in sillico analysis and experimental validation of interaction of RevKLM complex for Reveromycin A biosynthesis.
¡û²¬Â¼ ±Ñ¼£1¡¢º´Æ£¡Ê¼®ùõ¡Ë ͵Èþ1¡¢±ü¼ ±ÑÉ×2¡¢·§ºä ¿ò2¡¢Ä¹ÅÄ ÍµÇ·1¡¢¹â¶¶ ½ÓÆó1
¡ûEiji OKAMURA1, Yumi SHIOZAKI-SATO1, Hideo OKUMURA2, Takashi KUMASAKA2, Hiroyuki OSADA1, Shunji TAKAHASHI1
1Íý¸¦ CSRS¡¢2¹âµ±ÅÙ¸÷²Ê³Ø¸¦µæ¥»¥ó¥¿¡¼
1RIKEN CSRS, 2JASRI
2F02-06
2022/03/16 09:30
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ClassIB¥Æ¥ë¥Ú¥ó¹çÀ®¹ÚÁǤδð¼Á/¥Þ¥°¥Í¥·¥¦¥à¥¤¥ª¥ó·ë¹ç·¿Î©Âι½Â¤¤ò´ð¤Ë¤·¤¿ÊÑ°Û¹ÚÁDzòÀÏ
Mutant analysis of Class IB terpene synthase
¡û´äÊÒ ¾©¸ç1¡¢¶âËÜ ÁÔÊ¿2¡¢»°ÌÚ Ë®É×2¡¢¿¼°æ ¼þÌé2¡¢Æ£¶¶ ²í¹¨3¡¢ÉÊÅÄ Å¯Ïº4¡¢¾åÅÄ Â缡Ϻ1¡¢º´Æ£ ÅØ1
¡ûShogo Iwakata1, Souhei Kanemoto2, Kunio Miki2, Shuya Fukai2, Masahiro Fujihashi3, Tetsuro Shinada4, Daijiro Ueda1, Tsutomu Sato1
1¿·³ãÂ籡¼«Á³¡¢2µþÂ籡Íý¡¢3Âçºå°åÌôÂç¡¢4ºå»ÔÂ籡Íý
1Niigata Univ., 2Kyoto Univ., 3Osaka Medical and Pharmaceutical Univ., 4Osaka City Univ.
2F02-07
2022/03/16 09:30
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¥¯¥é¥¹IB¥Æ¥ë¥Ú¥ó¹çÀ®¹ÚÁǤΥ²¥Î¥à¥Þ¥¤¥Ë¥ó¥°
Genome mining of Class IB terpene synthases
¡ûÂçÄÍ À¸1¡¢Æ£¶¶ ²í¹¨2¡¢ÉÊÅÄ Å¯Ïº3¡¢¾åÅÄ Â缡Ϻ1¡¢º´Æ£ ÅØ1
¡ûIkiru OTSUKA1, Masahiro FUJIHASHI2, Tetsuro SHINADA3, Daijiro UEDA1, Tsutomu SATO1
1¿·³ãÂ籡¼«Á³¡¢2ºå°åÌôÂç¡¢3ºå»ÔÂ籡Íý
1Niigata Univ., 2Osaka Medical and Pharmaceutical Univ., 3Osaka City Univ.
2F02-08
2022/03/16 09:30
¥ß¡¼¥Æ¥£¥ó¥°¥ë¡¼¥à F
ΩÂι½Â¤¤Ë´ð¤Å¤¯¥¢¥ó¥Ö¥ì¥¤¥ó¹çÀ®¹ÚÁǤο¨ÇÞµ¡¹½²òÀϤȹ½Â¤°ÂÄê²½
Catalytic mechanism and structure stabilization of ambrein synthase based on the crystal structure
¡ûµµÃ« ÂÀ°ì1¡¢µ×ÊÝÅÄ ÃÒ̦2¡¢¾®»³ ͵¾´1¡¢»³ß· ͧÍÕ1¡¢¾åÅÄ Â缡Ϻ1¡¢ÉÊÅÄ Å¯Ïº3¡¢º´Æ£ ÅØ1
¡ûTaichi KAMEYA1, Tomomi KUBOTA2, Hiroaki KOYAMA1, Tomoha YAMAZAWA1, Daijiro UEDA1, Tetsuro SINADA3, Tsutomu SATO1
1¿·³ãÂ籡¼«Á³¡¢2»ºÁí¸¦¡¢3ºå»ÔÂ籡Íý
1Niigata Univ, 2AIST, 3Osaka City Univ
2F02-09
2022/03/16 09:30
¥ß¡¼¥Æ¥£¥ó¥°¥ë¡¼¥à F
Æóµ¡Ç½À­¥È¥ê¥Æ¥ë¥Ú¥ó/¥»¥¹¥¯¥¢¥Æ¥ë¥Ú¥ó´Ä²½¹ÚÁǤˤª¤±¤ë¥»¥¹¥¯¥¢¥Æ¥ë¥Ú¥ó´Ä²½¤Ë½ÅÍפʥ¢¥ß¥Î»À»Ä´ð¤Î²òÀÏ
Analysis of amino acid residues important for sesquarterpene cyclization in bifunctional triterpene/sesquarterpene cyclase
¡ûÁ¥ÄÅ è½¹á1¡¢Â뱩 Í¥¹á1¡¢ÉÊÅÄ Å¯Ïº2¡¢µµÃ« ÂÀ°ì1¡¢µ×ÊÝÅÄ ÃÒ̦3¡¢¾åÅÄ Â缡Ϻ1¡¢º´Æ£ ÅØ1
¡ûRika FUNATSU1, Yuka TAKABA1, Tetsuro SHINADA2, Taichi KAMEYA1, Tomomi KUBOTA3, Daijiro UEDA1, Tsutomu SATO1
1¿·³ãÂ籡¼«Á³¡¢2ºå»ÔÂ籡Íý¡¢3»ºÁí¸¦
1Niigata Univ., 2Osaka City Univ., 3AIST
2F02-10
2022/03/16 09:30
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Functional characterization of a novel bifunctional drimenol synthase of bacterial origin: A step toward the discovery of drimane sesquiterpenes in bacteria
¡ûNhu Ngoc Quynh Vo1, Yuhta Nomura2, Kiyomi Kinugasa1, Hiroshi Takagi1, Yumi Shiozaki-Sato1, Shunji Takahashi1
1RIKEN CSRS, Nat. Prod. Biosynth., 2RIKEN CSRS, Biomol. Charact.
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