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3F02-01
2022/03/17 09:30
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Discovery of new lucilactaene derivatives with potent antimalarial activity and their structure-activity relationship
¡ûIslam Adel Abdelhakim Amin1,2,3,4, Fauze Mahmud1,5,6, Motoyama Takayuki1, Nogawa Toshihiko1, Futamura Yushi1, Takahashi Shunji2,3, Osada Hiroyuki1
1Chemical biology, CSRS, RIKEN, 2Natural products biosynthesis unit, CSRS, RIKEN, 3Saitama Univ., 4Assiut Univ., 5INFORMM, USM, 6FSSA, UMS
3F02-02
2022/03/17 09:30
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Mode of action study of dihydrolucilactaene, a new highly potent antimalarial compound
¡ûFauze Mahmud1,2,3, Futamura Yushi1, Islam A. Abdelhakim1,4,5,6, Motoyama Takayuki1, Takahashi Shunji1,4,5, Ngit Shin Lai2, Osada Hiroyuki1
1Chemical Biology, RIKEN, CSRS, 2INFORMM, USM, 3FSSA, UMS, 4Natural Product Biosynthesis Research Unit, RIKEN, CSRS, 5Saitama Univ., 6Assiut Univ.
3F02-03
2022/03/17 09:30
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¹ÚÊì¥æ¥Ó¥­¥Á¥ó¥ê¥¬¡¼¥¼RSP5ÊÑ°Û³ô¤ò¹â²¹¥¹¥È¥ì¥¹²¼¤ÇÀ¸°é¤ò²óÉü¤µ¤»¤ëµ×»ü»ºàèàáͳÍè¤ÎÀ¸Êª³èÀ­Êª¼Á¤Îõº÷
Isolation of biologically active compounds that restore the groth of yeast ubiquitin ligase rsp5 A401E strain under high temperature stress from Kuji amber.
¡ûð¾ì À²Ìé1¡¢ÅÄÃæ Íè¼Â2¡¢¹âÌÚ Çî»Ë3¡¢±ÛÌî ¹­Àã4¡¢ÌÚ¼ ¸­°ì1,2
¡ûSeiya TANBA1, Kurumi TANAKA2, Hiroshi TAKAGI3, Hiroyuki KOSHINO4, Ken-ichi KIMURA1,2
1´ä¼êÂ硦ÇÀ¡¢2´ä¼êÂ籡¡¦Áí¹ç²Ê³Ø¡¢3ÆàÎÉÀèüÂ硦¥Ð¥¤¥ª¡¢4Íý¸¦CSRS
1Fac. of Agri. Iwate Univ., 2Grad. Sch. of Arts and Sci.Iwate Univ., 3Div. of Biol. Sci. NAIST, 4RIKEN CSRS
3F02-04
2022/03/17 09:30
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¤¬¤óºÙ˦¤ÎÃæ¿´ÂÎ¥¯¥é¥¹¥¿¥ê¥ó¥°Á˳²³èÀ­¤òÍ­¤¹¤ë kolavenic acid analog ¤Î³Æ¼ï¹³¤¬¤óºÞ¤È¤ÎÊ»ÍѸú²Ì
Combination effect of kolavenic acid analog having centrosome clustering inhibitory activity with various anticancer agents on cancer cells
¡û¸Å»³ ãµ®1¡¢üâ²°Éß Ë¾2¡¢¾®Ìî»û ÂóÌ´2¡¢²Ï¼ ¹¬ÃË2¡¢ÅòÀî ³Ê»Ë3,4¡¢ÅÐÅÄ Î´3,4¡¢ÌÚ¼ ¸­°ì1,2
¡ûTatsuki FURUYAMA1, Nozomi TAKAYASHIKI2, Takumu ONODERA2, Yukio KAWAMURA2, Masashi YUKAWA3,4, Takashi TODA3,4, Ken-ichi KIMURA1,2
1´ä¼êÂçÇÀ¡¢2´ä¼êÂ籡¡¦Áí¹ç²Ê³Ø¡¢3¹­ÅçÂ籡¡¦Åý¹çÀ¸Ì¿²Ê³Ø¡¢4¹­ÅçÂ硦·ò¹¯Ä¹¼÷ (HiHA)
1Fac. of Agri. Iwate Univ., 2Grad. Sch. of Arts and Sci. Iwate Univ., 3Grad. Sch. of Integrated Sch. for Life. Hirosima Univ., 4HiHA, Hiroshima Univ.
3F02-05
2022/03/17 09:30
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¥Ó¥ª¥Á¥óɸ¼±¥×¥í¡¼¥Ö¤òÍѤ¤¤¿¥×¥ë¥À¥¦¥ó¼Â¸³¤Ë¤è¤ëPF1171B¤ÎɸŪʬ»Ò¤Îõº÷
Screening of target molecules of PF1171B by pull-down experiments using its biotin-labeled probes
¡û¿¥ÅÄ Âç²Ï¡¢°ð³À ¾÷¡¢ÁýÅÄ Íµ°ì
¡ûTaiga Oda, Minoru Inagaki, Yuichi Masuda
»°½ÅÂ籡À¸Êª»ñ¸»³Ø
Graduate School of Bioresources, Mie University
3F02-06 ¥×¥í¥°¥é¥à¸¡º÷¥µ¥¤¥È¸ø³«»þ¤ÎÆâÍƤ«¤éÊѹ¹¤¬Æþ¤Ã¤Æ¤¤¤Þ¤¹
2022/03/17 09:30
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3²óÂоΤʤé¤Ó¤ËÊ¿¹Ô·¿A¦Â40¤Î3ÎÌÂÎ¥â¥Ç¥ë¤Î¹çÀ®¤Èµ¡Ç½²òÀÏ
Synthesis and characterization of trimer models of A¦Â40 with C3-symmetric or parallel structure
¡ûÆâÌî ÊâÈþ1¡¢Æþ¹¾ ͳÈþ1¡¢ÄÍÌî Àé¿Ò1¡¢ÀîÀ¥ ÂÙ¼£2¡¢×¢À¥ ¸­¼£2¡¢Æþ¹¾ °ì¹À1
¡ûAyumi UCHINO1, Yumi IRIE1, Chihiro TSUKANO1, Taiji KAWASE2, Kenji HIROSE2, Kazuhiro IRIE1
1µþÂ籡ÇÀ¡¢2ÆüËÜ¥¦¥©¡¼¥¿¡¼¥º
1Kyoto Univ., 2Nihon Waters K. K.
3F02-07
2022/03/17 09:30
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¥¢¥ß¥í¥¤¥É¦Â-40¤ÎÆÇÀ­£²ÎÌÂÎ¥â¥Ç¥ë¤Ë¤ª¤±¤ë¥ê¥ó¥«¡¼Ä¹¤Î¶Å½¸Ç½¤ÈºÙ˦ÆÇÀ­¤ËµÚ¤Ü¤¹±Æ¶Á
Effects of the length of the linker on the aggregative ability and cytotoxicity in the toxic dimer model of A¦Â40
¡ûÃÞ¸å ʸ³¾1¡¢Æþ¹¾ ͳÈþ1¡¢ÆâÌî ÊâÈþ1¡¢ÄÍÌî Àé¿Ò1¡¢ÀîÀ¥ ÂÙ»Ê2¡¢×¢À¥ ¸­¼£2¡¢Æþ¹¾ °ì¹À1
¡ûAYAKA CHIKUGO1, YUMI IRIE1, AYUMI UCHINO1, CHIHIRO TSUKANO1, TAIJI KAWASE2, KENJI HIROSE2, KAZUHIRO IRIE1
1µþÂçÇÀ¡¢2ÆüËÜ¥¦¥©¡¼¥¿¡¼¥º
1Kyoto Univ., 2Nihon Waters
3F02-08
2022/03/17 09:30
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¼çÀ®Ê¬Ê¬ÀϤò³èÍѤ·¤¿LC-MS¤Ë¤è¤ë ¥¢¥ß¥í¥¤¥É¦Â¶Å½¸Á˳²ºÞ¤Î¸úΨŪõº÷Ë¡
An efficient search method for Amyloid-¦Â aggregation inhibitors by LC-MS with principal component analysis
¡û²ÖÌÚ ¿ðÊæ1¡¢Â¼¾å °ìÇÏ1¡¢·´»Ê ͵¼ù2¡¢Æþ¹¾ °ì¹À1
¡ûMizuho HANAKI1, Kazuma MURAKAMI1, Hiroki GUNJI2, Kazuhiro IRIE1
1µþÂ籡ÇÀ¡¢2¥¢¥ë¥×¥¹ÌôÉʹ©¶È
1Kyoto Univ., 2Alps Pharmaceutical Ind. Co.,Ltd.
3F02-09
2022/03/17 09:30
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µ¡Ç½À­¿©ÉÊÀ®Ê¬¤Ë´Þ¤Þ¤ì¤ë¥Õ¥é¥Ü¥Î¥¤¥ÉÊú¹çÂΤιçÀ®¤È¥¢¥ß¥í¥¤¥É¦Â42¤ËÂФ¹¤ë¶Å½¸Á˳²³èÀ­
Synthesis and inhibitory activity against amyloid ¦Â42 aggregation of conjugated metabolites in functional food components
¡ûëÎØ ¸üÂÀ¡¢Â¼¾å °ìÇÏ¡¢Æþ¹¾ °ì¹À
¡ûKota Taniwa, Kazuma Murakami, Kazuhiro Irie
µþÂ籡ÇÀ
Grad. Agri. Kyoto Univ.
3F02-10 ¥×¥í¥°¥é¥à½¸¡¦Í׻ݽ¸¤ÎÆâÍƤ«¤éÊѹ¹¤¬Æþ¤Ã¤Æ¤¤¤Þ¤¹
2022/03/17 09:30
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Studies on chemical regulation of fungal denitrification toward global environmental conservation
¡ûQing CAI1, Masaki MATSUOKA1,2, Seiji MATSUOKA2, Kousiki MINO2, Toshie KAIZUKA2, Ashutosh KUMAR3, Keishi SENOO1,4, Kam Y. J. ZHANG3, Shinichi NISHIMURA1,4, Akihisa MATSUYAMA1,2, Minoru YOSHIDA1,2,4
1Dept. of Biotechnol., Univ. Tokyo, 2RIKEN CSRS, 3RIKEN BDR, 4CRIIM, UTokyo
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