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¥­¡¼¥ï¡¼¥É:G protein-coupled receptor ¤Î¸¡º÷·ë²Ì

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1G01-05
2023/03/14 09:00
¥ß¡¼¥Æ¥£¥ó¥°¥ë¡¼¥à G
Íå´Á²Ì (Siraitia grosvenorii) ͳÍè¥â¥°¥í¡¼¥ë¤Ë¤è¤ëÃÀ½Á»À¼õÍÆÂÎTGR5³èÀ­²½¤È¹â»éËÿ©ÀݼèKKAy¥Þ¥¦¥¹¤Î¹â·ìÅüÍÞÀ©ºîÍÑ
Mogrol derived from Siraitia grosvenorii activates the bile acid receptor TGR5 and suppresses hyperglycemia in high-fat diet-fed KKAy mice
¡ûÅÄÃæ ÀéÃÒ1¡¢¸¶ÅÄ Ä¾¼ù1,2¡¢¼¿ºê ¹­´î1¡¢»û²¬ ²Â¹¸1¡¢»Í¸µ ͥͤ3¡¢°ËÆ£ ͺÂÀ3¡¢ËÌÉ÷ ÃÒÌé1,2¡¢´¥ δ1,2¡¢Â¼ÅÄ Íº»Ê3¡¢´¥ Çî1,2,4¡¢»³ÃÏ Î¼°ì1,2
¡ûChisato TANAKA1, Naoki HARADA1,2, Hiroki URUSHIZAKI1, Yoshiaki TERAOKA1, Yusuke YOTSUMOTO3, Yuta ITO3, Tomoya KITAKAZE1,2, Takashi INUI1,2, Yuji MURATA3, Hiroshi INUI1,2,4, Ryoichi YAMAJI1,2
1ÂçºåÉÜÂ籡À¸Ì¿´Ä¶­¡¢2Âçºå¸øÂ籡ÇÀ¡¢3¥µ¥é¥ä³ô¼°²ñ¼Ò¡¢4Âç¼êÁ°Âç·ò¹¯±ÉÍÜ
1Osaka Pref. Univ., 2Osaka Metrop. Univ., 3Saraya Co. Ltd., 4Otemae Univ.
3A06-01
2023/03/16 13:00
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¹í¶ÝAspergillus oryzae¤Î¥¯¥é¥¹VI GPCR¤ÏRGS¥É¥á¥¤¥ó¤ò²ð¤·¤¿G¥¿¥ó¥Ñ¥¯¼Á¤ÎÉÔ³èÀ­²½¤òÄ̤¸¤Æ¶Ý³Ë·ÁÀ®¤òÉé¤ËÀ©¸æ¤¹¤ë
Class VI GPCRs in Aspergillus oryzae negatively regulate sclerotia formation via inactivation of G proteins by their RGS domains
¡ûºä¸µ ͦ·î1¡¢¶â Åìû¦1¡¢Í­²¬ ³Ø1,2
¡ûitsuki Sakamoto1, Dong min Kim1, Manabu Arioka1,2
1ÅìÂ籡¡¦ÇÀÀ¸²Ê¡¦±þÀ¸¹©¡¢2ÅìÂçCRIIM
1Dept. Biotechnol., Univ. Tokyo, 2CRIIM, UTokyo
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