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1F02-01
2023/03/14 09:30
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¥¢¥º¥é¥¯¥È¥ó¹çÀ®¹ÚÁǤε¡Ç½²òÀÏ
Elucidation of the mechanism for azlactone-forming enzyme
¡ûÀÄÌÚ µÁ¸÷¡¢Æî Êâ¼Â¡¢´ßËÜ ¿¿¼£¡¢ÅÏÊÕ ¸­Æó
¡ûYoshimitsu AOKI, Ayumi MINAMI, Shinji KISHIMOTO, Kenji WATANABE
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Univ. Shizuoka
1F02-02
2023/03/14 09:30
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Cladobotryum°¿¿¶Ý¤¬À¸»º¤¹¤ëFR901483¤ËÂФ¹¤ë¼«¸ÊÂÑÀ­µ¡¹½¤Î²òÌÀ
Self-resistance enzyme identified as a target of immunosuppressant (-)–FR901483
¡ûºäÌî ºù»Ò1¡¢Ã渶 ¼Â¶ê1¡¢Åļ Í¥°Í1¡¢º´Æ£ Æ»Âç1¡¢¸¶ ¹¬Âç1¡¢¶¶ËÜ Çî1¡¢TANG Yi2¡¢ÅÏÊÕ ¸­Æó1
¡ûSakurako SAKANO1, Miku NAKAHARA1, Yui TAMURA1, Michio SATO1, Kodai HARA1, Hiroshi HASHIMOTO1, Yi TANG2, Kenji WATANABE1
1ÀŲ¬¸©ÂçÌô¡¢2UCLA
1University of Shizuoka, 2University of California, Los Angeles
1F02-03
2023/03/14 09:30
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OSMACË¡¤Ë¤è¤ê¸«½Ð¤µ¤ì¤¿ÊüÀþ¶ÝͳÍèÅ·Á³Êª¤ÎÀ¸¹çÀ®¸¦µæ
Biosynthetic study on natural products from actinomycetes through an OSMAC methodology
¡û¾®ÎÓ Íµµ±1¡¢±óÆ£ ÎÆÂÀ1¡¢º´Æ£ Æ»Âç1¡¢Lopez Julius2¡¢ÌîÀî ½Óɧ2¡¢Ä¹ÅÄ ÍµÇ·1,2¡¢ÅÏÊÕ ¸­Æó1
¡ûYuki KOBAYASHI1, Ryota ENDO1, Michio SATO1, Julius LOPEZ2, Toshihiko NOGAWA2, Hiroyuki OSADA1,2, Kenji WATANABE1
1ÀŲ¬¸©Î©Âç³ØÌô¡¢2Íý¸¦´Ä¶­»ñ¸»¥»
1Department of Pharmaceutical Sciences, University of Shizuoka, 2RIKEN
1F02-04
2023/03/14 09:30
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I·¿¥Ý¥ê¥±¥Á¥É¹çÀ®¹ÚÁǤˤª¤±¤ë¥±¥È¹çÀ®¹ÚÁÇÍÍæú»À¹ÚÁǤȥ¢¥·¥ë¥­¥ã¥ê¥¢¥¿¥ó¥Ñ¥¯¼Á´ÖÁê¸ßºîÍѤβòÌÀ
Protein-protein interaction between ketosynthase-like decarboxylase and acyl carrier protein in type I polyketide synthases
¡ûÀé¿û ÂÀ°ì¡¢µÜ±Ê ¸²Àµ¡¢¹©Æ£ »Ëµ®¡¢¹¾¸ý Àµ
¡ûTaichi CHISUGA, AKIMASA MIYANAGA, FUMITAKA KUDO, TADASHI EGUCHI
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Tokyo Tech.
1F02-05
2023/03/14 09:30
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¥Þ¥¯¥í¥é¥¯¥¿¥à¹³À¸Êª¼Á¥¯¥ì¥ß¥Þ¥¤¥·¥óÀ¸¹çÀ®¤Ë¤ª¤±¤ëæ¿å¹ÚÁǤȥ¢¥·¥ë¥­¥ã¥ê¥¢¥¿¥ó¥Ñ¥¯¼Á´Ö¤ÎÁê¸ßºîÍѲòÀÏ
Protein-protein interaction between dehydratase and acyl carrier protein in the biosynthesis of macrolactam antibiotic cremimycin
¡û¾®ÅÄÀÚ Éö¡¢Àîùõ ÂçÊå¡¢Àé¿û ÂÀ°ì¡¢µÜ±Ê ¸²Àµ¡¢¹©Æ£ »Ëµ®¡¢¹¾¸ý Àµ
¡ûKAEDE KOTAGIRI, DAISUKE KAWASAKI, TAICHI CHISUGA, AKIMASA MIYANAGA, FUMITAKA KUDO, TADASHI EGUCHI
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Tokyo Tech.
1F02-06
2023/03/14 09:30
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ValidamycinA¤ÎÀ¸¹çÀ®¤Ë¤ª¤±¤ëµ¿»÷Åüž°Ü¹ÚÁÇVldE¤ÎÈ¿±þµ¡¹½
Catalytic Mechanism of VldE, a Pseudoglycosyltransferase from the Validamycin Biosynthetic Pathway
¡û³ÑÅÄ µ£1¡¢Abuelizz Hatem1¡¢Samadi Arash1¡¢°¤Éô °êϯ2¡¢Mahmud Taifo1
¡ûTakeshi TSUNODA1, Hatem Abuelizz1, Arash Samadi1, Ikuro ABE2, Taifo Mahmud1
1¥ª¥ì¥´¥ó½£Î©Âç³ØÌô¡¢2ÅìÂ籡Ìô
1Oregon State Univ., 2The Univ. of Tokyo
1F02-07
2023/03/14 09:30
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Discovery of an unprecedented use of thiamine diphosphate in natural product biosynthesis
¡ûYuxun ZHU1, Taro Shiraishi1,2, Tomohisa Kuzuyama1,2
1Grad. Sch. Agri. Life Sci., UTokyo, 2CRIIM, UTokyo
1F02-08
2023/03/14 09:30
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Biosynthesis of the acyl side chain in the nucleoside antibiotic A-94964 by unusual Type I polyketide synthase of Streptomyces sp. SANK 60404
¡ûHAO XU1, Taro Shiraishi1,2, Tomohisa Kuzuyama1,2
1Grad. Sch. Agri. Life Sci., UTokyo, 2CRIIM, UTokyo
1F02-09
2023/03/14 09:30
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Screening method toward specific ClbP inhibitors
¡ûTao Zhou1,2, Michio Sato2, Kenji Watanabe1,2
1Adenoprevent Co., Ltd., 2Department of Pharmaceutical Sciences, University of Shizuoka
1F02-10
2023/03/14 09:30
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ÈùºÙÁôÎàͳÍèDHA¹çÀ®¹ÚÁǤÎketosynthase¥É¥á¥¤¥ó¤Îµ¡Ç½²òÀÏ
Dissecting Ketosynthase domains in Microalgal Polyunsaturated Fatty Acid Synthase
¡ûÈø·Á ³¤ÅÍ1¡¢¾®ÎÓ Èôͪ1¡¢º´Æ£ ¹¯¼£2¡¢´Ý»³ ÀéÅÐÀª3¡¢ßÀÌî µÈ½½3¡¢¾®³Þ¸¶ ÂÙ»Ö2¡¢ÂçÍø Å°2
¡ûKaito OGATA1, Hiyu KOBAYASHI1, Yasuharu SATOH2, Chitose MARUYAMA3, Yoshimitsu HAMANO3, Yasushi OGASAWARA2, Tohru DAIRI2
1ËÌÂ籡Áí²½¡¢2ËÌÂ籡¹©¡¢3Ê¡°æ¸©Â籡À¸Êª»ñ¸»
1Grad. Sch. Chem. Sci. Eng., Hokkaido Univ., 2Grad. Sch. Eng., Hokkaido Univ., 3Fukui Pref. Univ.
1F02-11
2023/03/14 09:30
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¿·µ¬¥Ú¥×¥Á¥É¥¨¥Ô¥á¥é¡¼¥¼MslH¤ÎÈ¿±þµ¡¹½¤Î²òÀÏ
Mechanistic study of novel peptide epimerase MslH
¡ûÀî¾å ÆÆ»Î1¡¢ÃæÅè Í¥2¡¢¿¹ÅÄ ÍιÔ2¡¢¾®³Þ¸¶ ÂÙ»Ö3¡¢ÂçÍø Å°3
¡ûAtsushi KAWAKAMI1, Yu NAKASHIMA2, Hiroyuki MORITA2, Yasushi OGASAWARA3, Tohru DAIRI3
1ËÌÂ籡Áí²½¡¢2ÉÙ»³Âç°åÌôÁí¹ç¸¦¡¢3ËÌÂ籡¹©
1Grad. Sch. Chem. Sci. Eng., Hokkaido Univ., 2Inst. Nat. Med., Toyama Univ., 3Grad. Sch. Eng., Hokkaido Univ.
1F02-12
2023/03/14 09:30
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¿·µ¬¥Ú¥×¥Á¥É¥¨¥Ô¥á¥é¡¼¥¼MurL¤ÎÈ¿±þµ¡¹½²òÀÏ
Reaction mechanism of novel peptide epimerase MurL
¡ûËÙÆâ Ëï´õ1¡¢ÃæÈø ͥʸ1¡¢ÃæÅè Í¥2¡¢¿¹ÅÄ ÍιÔ2¡¢¾®³Þ¸¶ ÂÙ»Ö1¡¢ÂçÍø Å°1
¡ûMasaki HORIUCHI1, Masafumi NAKAO1, Yu NAKASHIMA2, Hiroyuki MORITA2, Yasushi OGASAWARA1, Tohru DAIRI1
1ËÌÂ籡¹©¡¢2ÉÙ»³Âç°åÌôÁí¹ç¸¦
1Grad. Sch. Eng., Hokkaido Univ., 2Inst. Nat. Med., Toyama Univ.
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